You can't target search campaigns to remarketing audiences.

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Match types cannot be changed manually.
You can't have a list of minus words for search phrases. There is an analogue of minus topics, but they don't work the same way as minus words.
A maximum budget is set for the campaign, but the system itself decides which strategy to use and what rate to set.


Smart Display Campaigns:

You can't select targeting settings, which could result in your ads being shown to irrelevant users.
It is impossible to evaluate the effectiveness of creatives and images used in advertising, you will not know which images or elements of advertising text work well and which negatively affect the results.
You can't choose which devices your ads will be saudi arabia email list shown on and evaluate the effectiveness of each device.
You can't manually target audiences based on interests.
You cannot add exclusion locations, which means your ads are likely to be shown to irrelevant users.


Smart Shopping Campaigns:

You cannot use negative keyword lists.
Device targeting cannot be used.
You cannot set rates for a product group.
You cannot target specific devices or choose specific placements for your ads.