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TruTarget ® : Efficient target deconvolution and binding site mapping in drug discovery
Biognosys' TrueTarget platform leverages limited proteolysis mass spectrometry (LiP-MS) to facilitate the identification and validation of drug targets. The initial poster, in collaboration with InterAx, demonstrates TrueTarget's unique capabilities in deconvoluting the target of a G protein-coupled receptor (GPCR) antagonist, mapping its binding sites, and providing structural insights into the mechanism of action. The second poster, in collaboration with Samsar Therapeutics, explains how target deconvolution with TrueTarget, followed by unbiased proteome profiling with TrueDiscovery, enables efficient identification and validation of target proteins and improved understanding of biological systems in the development of new therapeutics.

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